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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 12.42
Human Site: S428 Identified Species: 18.22
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 S428 A S R T Q D P S S P G T T P P
Chimpanzee Pan troglodytes XP_525468 559 61460 S428 A S R T Q D P S S P G T T P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 P538 H Q G S S P G P R L A E G T P
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 S435 S N R T Q D P S S P C T T P S
Rat Rattus norvegicus NP_001019912 572 62715 S435 S N R I Q D P S S P C T T P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 T436 V R T R D P G T P S P P L Q A
Chicken Gallus gallus Q5R1S9 566 62559 L435 T S L S T P T L Q P K T P V A
Frog Xenopus laevis Q8QFR2 1013 112021 N595 V D R L K E Q N V T K D S K P
Zebra Danio Brachydanio rerio NP_998177 236 26626 F107 E P E Q T P T F Q E E E D A Q
Tiger Blowfish Takifugu rubipres O42611 1025 111838 G514 P G Q A P P L G L R P S Q D P
Fruit Fly Dros. melanogaster NP_610589 747 83376 E482 S P K T K A S E E E K P T P I
Honey Bee Apis mellifera XP_624307 452 51453 A323 L P Y R M V F A V A T Q H S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 E466 V G G N R V K E A K R I T P V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 P377 E N E E L G Q P H I L P G S K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 L358 P N A S Y L A L S S Q D G Y C
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 K339 T C Q K S V L K L P Y K L V F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 6.6 N.A. 73.3 66.6 N.A. 0 20 13.3 0 6.6 20 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 80 N.A. 6.6 26.6 40 0 20 40 6.6 N.A. 26.6
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 6.6 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 7 7 0 7 7 7 7 7 7 0 0 7 13 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 13 0 0 0 7 % C
% Asp: 0 7 0 0 7 25 0 0 0 0 0 13 7 7 0 % D
% Glu: 13 0 13 7 0 7 0 13 7 13 7 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 7 % F
% Gly: 0 13 13 0 0 7 13 7 0 0 13 0 19 0 0 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 7 0 7 0 0 13 % I
% Lys: 0 0 7 7 13 0 7 7 0 7 19 7 0 7 7 % K
% Leu: 7 0 7 7 7 7 13 13 13 7 7 0 13 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 25 0 7 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 13 19 0 0 7 32 25 13 7 38 13 19 7 38 32 % P
% Gln: 0 7 13 7 25 0 13 0 13 0 7 7 7 7 7 % Q
% Arg: 0 7 32 13 7 0 0 0 7 7 7 0 0 0 0 % R
% Ser: 19 19 0 19 13 0 7 25 32 13 0 7 7 13 13 % S
% Thr: 13 0 7 25 13 0 13 7 0 7 7 32 38 7 0 % T
% Val: 19 0 0 0 0 19 0 0 13 0 0 0 0 13 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 7 0 0 0 0 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _